Saturday, March 18, 2006

9/11 Impact On Mesothelioma: Researchers Worry

Researchers and experts are concerned about the possible impact of the 9/11 disaster on mesothelioma in the coming years and decades.

It is generally agreed that the large amounts of asbestos released during the 9/11 disaster will have a substantial impact on the number of new mesothelioma cases in the United States in years to come.

9/11 concerns over new mesothelioma cases are further complicated by the fact that it usually takes 20 to 40 years after asbestos exposure for mesothelioma cases to start developing. Currently there are about 3,500 mesothelioma cases being treated annually in the country.

And even where mesothelioma does occur, it is not known exactly how many of these patients will be actually treated because there is usually a large number who are misdiagnosed as having metastatic adenocarcinoma which is another different form of cancer. This could further worsen the impact of 9/11 on new mesothelioma cases over the next couple of decades.

Then there are the usual problems that hinder treatment of mesothelioma like the medical community not bothering to refer patients to centers where potentially curative treatment can be given because it is generally believed that the disease has no known cure. The truth is that although mesothelioma experts are far from having a cure for all patients, recent developments of more effective treatments including radical surgery and advanced radiotherapeutic modalities now offer much better odds for longer survival to patients suffering from mesothelioma.

Before 9/11, researchers had expected the number of new mesothelioma cases to peak in the next few years and probably begin to fall. More so because of the major asbestos control initiatives of the 1970s.

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Saturday, March 11, 2006

Mesothelioma Treatment Option: Why Is The Removal Of The Lung And Other Organs Necessary?

One of the most successful Mesothelioma treatment options involves the removal of the lung and other organs via surgery. However many patients and their loved ones do not quite understand why this is necessary.

This Mesothelioma treatment option is necessary and is one of the most successful because the disease usually starts in the lining of the inner chest wall and the lining that covers the diaphragm. This is called the parietal pleura. The disease then grows into the lining that covers the lung (visceral pleura).

Because it is impossible to separate the visceral pleura from the lung so as to remove the Mesothelioma cancer, there is no option but treatment through the removal of the lung. Secondly it is also important to note that Mesothelioma often attacks the lung tissue so the only way to completely remove the tumor is by removing the lung.

Quality of life for patients after this Mesothelioma treatment option is difficult to predict. Many people may suffer a degree of shortness of breath, which incidentally is also, one of the symptoms of the disease before surgery. Also because the surgery involves a large incision and sometimes portions of the rib are also taken out, many patients suffer a lot of pain after the surgery, however this is usually quickly controlled by pain medication.

However many times this Mesothelioma treatment option results in a big improvement, especially if surgeons are able to properly remove the tumor. In fact many patients are able to breath a lot better with one lung. The reason is because of the relief of tumor compression on the lung and the related restriction of chest wall movement.

Friday, March 10, 2006

New Mesothelioma Treatment Research Shows Promise

New mesothelioma treatment research to determine if chemotherapy before surgery and radiation can prevent mesothelioma recurrence could provide a major step forward for the treatment of this rare cancer of the lining of the chest caused by exposure to asbestos.

This new mesothelioma treatment study is an attempt to build on previous clinical trials that have shown promise at M.D. Anderson which involved extra pleural pneumonectomy (EPP) surgery where the affected lung and lining of the chest are removed. This is followed by Intensity modulated radiotherapy (IMRT).

What is really unique about this new mesothelioma treatment study is the fact that this is the first trial to investigate the use of chemotherapy before surgery and radiation.

Results Of Previous Trials Of This New Mesothelioma Treatment

Previous trials of this new mesothelioma treatment involving extrapleural pneumonectomy and IMRT was 90 per cent effective in preventing a local recurrence in patients. However about half the patients who underwent the trials got a recurrence in a different location. Quite often, this was the other lung or another part of the body.

Researchers into this new mesothelioma treatment add that chemotherapy before surgery and radiation usually reduce the possibility of the cancer spreading to another area away from the original site.

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Latest Mesothelioma Research: Combination Improves Survival

The following mesothelioma research findings were reported in a recent issue of the Journal of Clinical Oncology. Mesothelioma researchers have reported that combining Tomudex (raltitrexed) and Platinol (cisplatin) has shown amazing results in the improved survival of patients suffering from the rare Malignant pleural mesothelioma which is caused by habitual exposure to asbestos.

According to the mesothelioma research findings reported in the journal, the combination of the two treatments dramatically improves the survival of patients compared to the use of Platinol alone.

These mesothelioma research findings emerged from a randomized phase III trial.

Patients suffering from this rare mesothelioma usually experience shortness of breath, cough, pain, fatigue and loss of appetite. This new mesothelioma research findings are all the more encouraging because this type of cancer has proved to be resistant to most therapies such as surgery, chemotherapy on its' own and even when combined with radiation.

What usually complicates matters further is the fact that usually patients are not aware of the fact that they are suffering from malignant pleural mesothelioma until the disease has already progressed to a very advanced stage where treatment with surgery or radiation is no longer a viable option.

That is why the identification of treatment that can improve survival as well as quality of life in patients, as this mesothelioma research promises, is so significant.

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